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Rab3C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55288

Novus Biologicals, part of Bio-Techne
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NBP2-55288
NBP2-55288-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ESLETDPAITAAKQNTRLKETPPPPQPNCAC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Rab3C Antibody

Immunocytochemistry/ Immunofluorescence: Rab3C Antibody [NBP2-55288]

Immunocytochemistry/ Immunofluorescence: Rab3C Antibody [NBP2-55288]

Immunocytochemistry/Immunofluorescence: Rab3C Antibody [NBP2-55288] - Staining of human cell line HeLa shows localization to cytosol.
Immunohistochemistry-Paraffin: Rab3C Antibody [NBP2-55288]

Immunohistochemistry-Paraffin: Rab3C Antibody [NBP2-55288]

Immunohistochemistry-Paraffin: Rab3C Antibody [NBP2-55288] - Staining in human cerebral cortex and kidney tissues using anti-RAB3C antibody. Corresponding RAB3C RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Rab3C Antibody [NBP2-55288]

Immunohistochemistry-Paraffin: Rab3C Antibody [NBP2-55288]

Immunohistochemistry-Paraffin: Rab3C Antibody [NBP2-55288] - Staining of human cerebral cortex shows high expression.

Applications for Rab3C Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rab3C

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary.

Alternate Names

RAB3C, member RAS oncogene family, ras-related protein Rab-3C

Gene Symbol

RAB3C

Additional Rab3C Products

Product Documents for Rab3C Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Rab3C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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