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Rab3D Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-3337

Novus Biologicals, part of Bio-Techne
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NB120-3337
NB120-3337-0.025mg

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptide corresponding to residues M(1) A S A S E P P A S P R D A A D Q N(18) of rat RAB3D.

Specificity

Detects recombinant mouse rab 3D. This does not detect rab 3A, 3B, or 3C.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Rab3D Antibody

Immunocytochemistry/ Immunofluorescence: Rab3D Antibody [NB120-3337]

Immunocytochemistry/ Immunofluorescence: Rab3D Antibody [NB120-3337]

Immunocytochemistry/Immunofluorescence: Rab3D Antibody [NB120-3337] - IF analysis of RAB3D was performed using 70% confluent log phase 3T3-L1 cells.

Applications for Rab3D Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Western Blot

2.0 ug/ml
Application Notes
WB: Detects an approx. 29 kDa protein representing recombinant mouse Rab 3D.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Rab3D

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.

Alternate Names

D2-2, GOVras-related protein Rab-3D, RAB16glioblastoma overexpressed, RAB3D, member RAS oncogene family, RAD3DRab3D upregulated with myeloid differentiation

Entrez Gene IDs

19340 (Mouse)

Gene Symbol

RAB3D

Additional Rab3D Products

Product Documents for Rab3D Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Rab3D Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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