Rabphilin 3A [p Ser234] Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-743

Novus Biologicals, part of Bio-Techne
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NB300-743
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Key Product Details

Species Reactivity

Validated:

Rat

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Rabphilin 3A Antibodies »

Product Specifications

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 conjugated to KLH. Accession # P47709

Modification

p Ser234

Specificity

Specific for endogenous levels of the ~82 kDa Rabphilin 3A protein phosphorylated at Ser234. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

82 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Rabphilin 3A [p Ser234] Antibody

Western Blot: Rabphilin 3A [p Ser234] Antibody [NB300-743]

Western Blot: Rabphilin 3A [p Ser234] Antibody [NB300-743]

Western Blot: Rabphilin 3A [p Ser234] Antibody [NB300-743] - Western blot of brain lysate showing specific immunolabeling of the ~82k rabphilin 3A phosphorylated at Ser234.

Applications for Rabphilin 3A [p Ser234] Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:400

Immunohistochemistry

1:400

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Rabphilin 3A

Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994;Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease(Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995;Foletti and Scheller, 2001).

Alternate Names

Exophilin-1, KIAA0985exophilin-1, rabphilin, rabphilin 3A homolog (mouse), rabphilin-3A

Entrez Gene IDs

19894 (Mouse); 171039 (Rat)

Gene Symbol

RPH3A

UniProt

P47709 (Rat)

Additional Rabphilin 3A Products

Product Documents for Rabphilin 3A [p Ser234] Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Rabphilin 3A [p Ser234] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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