Rabphilin 3A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87940

Novus Biologicals, part of Bio-Techne
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NBP1-87940
NBP1-87940-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Rabphilin 3A Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Rabphilin 3A Antibody

Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940]

Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940]

Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Analysis in human cerebral cortex and skeletal muscle tissues. Corresponding Rabphilin 3A RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940]

Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940]

Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940]

Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940]

Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human cerebellum shows moderate positivity in neuropil.
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Applications for Rabphilin 3A Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rabphilin 3A

Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994; Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995; Foletti and Scheller, 2001).

Alternate Names

Exophilin-1, KIAA0985exophilin-1, rabphilin, rabphilin 3A homolog (mouse), rabphilin-3A

Gene Symbol

RPH3A

Additional Rabphilin 3A Products

Product Documents for Rabphilin 3A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Rabphilin 3A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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