Rad23 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52942

Novus Biologicals, part of Bio-Techne
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NBP1-52942
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Rad23 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to RAD23A(RAD23 homolog A (S. cerevisiae)) The peptide sequence was selected from the middle region of RAD23A. Peptide sequence GIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQFQNMRQVIQQ. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Rad23 Antibody

Western Blot: Rad23 Antibody [NBP1-52942]

Western Blot: Rad23 Antibody [NBP1-52942]

Western Blot: hHR23A Antibody [NBP1-52942] - Titration: 2.5ug/ml Positive Control: Jurkat cell lysate.
Immunohistochemistry-Paraffin: Rad23 Antibody [NBP1-52942]

Immunohistochemistry-Paraffin: Rad23 Antibody [NBP1-52942]

Immunohistochemistry-Paraffin: hHR23A Antibody [NBP1-52942] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification.

Applications for Rad23 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rad23

RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Alternate Names

hHR23

Gene Symbol

RAD23A

UniProt

P54725

Additional Rad23 Products

Product Documents for Rad23 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Rad23 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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