Rad50 Antibody (S05-5H6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19512

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19512-100ul
NBP3-19512-50ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-5H6

Concentration

0.3 mg/ml

View all Rad50 Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Rad50 (Uniprot # Q92878)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

154 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Rad50 Antibody (S05-5H6)

Western Blot: Rad50 Antibody (S05-5H6) [NBP3-19512]

Western Blot: Rad50 Antibody (S05-5H6) [NBP3-19512]

Western Blot: Rad50 Antibody (S05-5H6) [NBP3-19512] - Western blot detection of Rad50 in K562, Hela cell lysates using NBP3-19512 (1:1000 diluted). Predicted band size: 154kDa. Observed band size: 154kDa.

Applications for Rad50 Antibody (S05-5H6)

Application
Recommended Usage

Western Blot

1/2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rad50

Rad50 is a 153kDa protein that associates with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, the complex translocates to the nucleus of damaged cells, binds DNA, and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. Overall, Rad50 is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination.

Alternate Names

DNA repair protein RAD50, EC 3.6, EC 3.6.1.15, EC 3.6.3, EC 3.6.3.27, hRAD50, NBSLD, RAD50 (S. cerevisiae) homolog, RAD50 homolog (S. cerevisiae), RAD502, RAD50-2

Gene Symbol

RAD50

Additional Rad50 Products

Product Documents for Rad50 Antibody (S05-5H6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Rad50 Antibody (S05-5H6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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