RAIDD/CRADD Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77061

Novus Biologicals, part of Bio-Techne
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NBP1-77061
NBP1-77061-0.025mg
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CRADD Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid peptide near the center of human RAIDD. The immunogen is located within amino acids 90 - 140 of RAIDD. Amino Acid Squence: AGDRLTGIPSHILNSSPSD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RAIDD/CRADD Antibody - BSA Free

Western Blot: RAIDD/CRADD AntibodyBSA Free [NBP1-77061]

Western Blot: RAIDD/CRADD AntibodyBSA Free [NBP1-77061]

Western Blot: RAIDD/CRADD Antibody [NBP1-77061] - Whole cell lysates from HeLa (H) or K562 (K) cells with RAIDD antibody at 1:500 dilution.
Immunocytochemistry/ Immunofluorescence: RAIDD/CRADD Antibody - BSA Free [NBP1-77061]

Immunocytochemistry/ Immunofluorescence: RAIDD/CRADD Antibody - BSA Free [NBP1-77061]

Immunocytochemistry/Immunofluorescence: RAIDD/CRADD Antibody [NBP1-77061] - Immunofluorescence of RAIDD/CRADD in Hela cells with RAIDD/CRADD antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: RAIDD/CRADD Antibody - BSA Free [NBP1-77061]

Immunocytochemistry/ Immunofluorescence: RAIDD/CRADD Antibody - BSA Free [NBP1-77061]

Immunocytochemistry/Immunofluorescence: RAIDD/CRADD Antibody [NBP1-77061] - Immunofluorescence of RAIDD in Hela cells with RAIDD antibody at 20 ug/mL.
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Applications for RAIDD/CRADD Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5-20 ug/mL

Western Blot

0.5-1 ug/mL
Application Notes
A 22 kDa band should be detected in Western Blot.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRADD

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals1,3. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.

Long Name

CASP2 and RIPK1 Domain Containing Adaptor With Death Domain

Alternate Names

RAIDD

Gene Symbol

CRADD

UniProt

AAB42217 (Human)

Additional CRADD Products

Product Documents for RAIDD/CRADD Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RAIDD/CRADD Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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