RASA3 Antibody (1F11)

Novus Biologicals, part of Bio-Techne | Catalog # H00022821-M01

Novus Biologicals, part of Bio-Techne
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H00022821-M01-100ug
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1F11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RASA3 Antibodies »

Product Specifications

Immunogen

RASA3 (AAH47242, 725 a.a. ~ 834 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI

Reactivity Notes

Human. Other species not tested.

Specificity

RASA3 - RAS p21 protein activator 3

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for RASA3 Antibody (1F11)

Western Blot: RASA3 Antibody (1F11) [H00022821-M01]

Western Blot: RASA3 Antibody (1F11) [H00022821-M01]

Western Blot: RASA3 Antibody (1F11) [H00022821-M01] - Analysis of RASA3 expression in transfected 293T cell line by RASA3 monoclonal antibody (M01), clone 1F11.Lane 1: RASA3 transfected lysate (Predicted MW: 95.7 KDa).Lane 2: Non-transfected lysate.
Sandwich ELISA: RASA3 Antibody (1F11) [H00022821-M01] - Detection limit for recombinant GST tagged RASA3 is approximately 0.3ng/ml as a capture antibody.

Applications for RASA3 Antibody (1F11)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: RASA3

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Alternate Names

GAP1(IP4BP), GAP1IP4BP, GAPIII, GTPase activating protein III, inositol 13,4,5-tetrakisphosphate-binding protein, Ins P4-binding protein, Ins(13,4,5)P4-binding protein, MGC46517, MGC47588, ras GTPase-activating protein 3, RAS p21 protein activator 3

Entrez Gene IDs

22821 (Human)

Gene Symbol

RASA3

OMIM

605182 (Human)

UniProt

AAH47242 (Human)

Additional RASA3 Products

Product Documents for RASA3 Antibody (1F11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RASA3 Antibody (1F11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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