Rat KOR Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB8867

Recombinant Monoclonal Antibody.
R&D Systems, part of Bio-Techne
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MAB8867
MAB8867-SP
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Key Product Details

Species Reactivity

Rat

Applications

Immunocytochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1123A

View all KOR Antibodies »

Product Specifications

Immunogen

Rat KOR N-terminal synthetic peptide
Accession # P34975

Specificity

Detects rat KOR in direct ELISAs.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Rat KOR Antibody

KOR antibody in CHO Chinese Hamster Cell Line by Immunocytochemistry (ICC).

KOR in CHO Chinese Hamster Cell Line.

KOR was detected in immersion fixed CHO Chinese hamster ovary cell line transfected with KOR using Rabbit Anti-Rat KOR Monoclonal Antibody (Catalog # MAB8867) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rabbit IgG Secondary Antibody (red; Catalog # NL004) and counterstained with DAPI (blue). Specific staining was localized to plasma membrane and cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Applications for Rat KOR Antibody

Application
Recommended Usage

Immunocytochemistry

8-25 µg/mL
Sample: Immersion fixed CHO Chinese hamster ovary cell line transfected with KOR

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: KOR

KOR is a 45 kDa 7TM opioid receptor that is primarily expressed in the central nervous system and peripheral visceral pain sensory nerves. Following ligation by dynorphin peptides, KOR signaling induces analgesia, dysphoria, diuresis, and increased feeding desire. KOR also exerts neuroprotective and anti-inflammatory effects. Human KOR shares 94% amino acid sequence identity with mouse and rat KOR.

Long Name

Kappa Opioid Receptor

Alternate Names

OPRK1, Oprk2, R21

Entrez Gene IDs

4986 (Human); 18387 (Mouse); 29335 (Rat)

Gene Symbol

OPRK1

UniProt

P34975

Additional KOR Products

Product Documents for Rat KOR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Rat KOR Antibody

For research use only

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