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RB associated KRAB repressor Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55962

Novus Biologicals, part of Bio-Techne
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NBP2-55962
NBP2-55962-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EYNECMEALDNEAVFIAHKRAYIGEKPYEWNDSGPDFIQMSNFNAYQRSQMEMKPF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RB associated KRAB repressor Antibody

Immunocytochemistry/ Immunofluorescence: RB associated KRAB repressor Antibody [NBP2-55962]

Immunocytochemistry/ Immunofluorescence: RB associated KRAB repressor Antibody [NBP2-55962]

Immunocytochemistry/Immunofluorescence: RB associated KRAB repressor Antibody [NBP2-55962] - Staining of human cell line MCF7 shows localization to nucleoplasm.

Applications for RB associated KRAB repressor Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RB associated KRAB repressor

RB associated KRAB repressor, also known as ZNF769, consists of a 83 kDa 714 and a shorter 12 kDa 113 isoform. Its function is to promote AR-dependent transcription by encoding a nuclear protein. Current research on RB associated KRAB repressor is being conducted in its relationship to retinoblastoma, hyperaldosteronism and familial hyperaldosteronism. RB associated KRAB repressor is known to interact with SUMO1, RB1, AR and SMARCAD1.

Alternate Names

hRBaK, RB-associated KRAB repressor, RB-associated KRAB zinc finger, RB-associated KRAB zinc finger protein, ZNF769Zinc finger protein 769

Gene Symbol

RBAK

Additional RB associated KRAB repressor Products

Product Documents for RB associated KRAB repressor Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RB associated KRAB repressor Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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