RBMS3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89497

Novus Biologicals, part of Bio-Techne
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NBP1-89497
NBP1-89497-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RBMS3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MNHLSLGTTGTIQSQDRIMILHQLLCQYMTAAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RBMS3 Antibody

Western Blot: RBMS3 Antibody [NBP1-89497]

Western Blot: RBMS3 Antibody [NBP1-89497]

Western Blot: RBMS3 Antibody [NBP1-89497] - Analysis in human cell line U-2 OS and human cell line HEK 293.
Immunocytochemistry/ Immunofluorescence: RBMS3 Antibody [NBP1-89497]

Immunocytochemistry/ Immunofluorescence: RBMS3 Antibody [NBP1-89497]

Immunocytochemistry/Immunofluorescence: RBMS3 Antibody [NBP1-89497] - Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
Immunohistochemistry-Paraffin: RBMS3 Antibody [NBP1-89497]

Immunohistochemistry-Paraffin: RBMS3 Antibody [NBP1-89497]

Immunohistochemistry-Paraffin: RBMS3 Antibody [NBP1-89497] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Applications for RBMS3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RBMS3

The protein encoded by the RBMS3 gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternate Names

RNA binding motif, single stranded interacting protein 3, RNA-binding protein, single stranded interacting protein, single-stranded-interacting protein 3

Gene Symbol

RBMS3

Additional RBMS3 Products

Product Documents for RBMS3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RBMS3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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