RCAN1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-94137

Novus Biologicals, part of Bio-Techne
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NBP2-94137-0.02ml
NBP2-94137-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RCAN1 Antibodies »

Product Summary for RCAN1 Antibody - BSA Free

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of human RCAN1 (NP_004405.3). DLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RCAN1 Antibody - BSA Free

Western Blot: RCAN1 AntibodyBSA Free [NBP2-94137]

Western Blot: RCAN1 AntibodyBSA Free [NBP2-94137]

Western Blot: RCAN1 Antibody [NBP2-94137] - Analysis of extracts of various cell lines, using RCAN1 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 90s.
Immunohistochemistry-Paraffin: RCAN1 Antibody - BSA Free [NBP2-94137]

Immunohistochemistry-Paraffin: RCAN1 Antibody - BSA Free [NBP2-94137]

Immunohistochemistry-Paraffin: RCAN1 Antibody [NBP2-94137] - Immunohistochemistry of paraffin-embedded rat heart using RCAN1 Rabbit pAb (NBP2-94137) at dilution of 1:150 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry-Paraffin: RCAN1 Antibody - BSA Free [NBP2-94137]

Immunohistochemistry-Paraffin: RCAN1 Antibody - BSA Free [NBP2-94137]

Immunohistochemistry-Paraffin: RCAN1 Antibody [NBP2-94137] - Immunohistochemistry of paraffin-embedded human brain using RCAN1 Rabbit pAb (NBP2-94137) at dilution of 1:150 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
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Applications for RCAN1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RCAN1

RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. RCAN1 is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for RCAN1.

Alternate Names

Adapt78, calcipressin-1, calcium and oxidant-inducible mRNA, Down syndrome candidate region 1, Down syndrome critical region gene 1, Down syndrome critical region protein 1, DSC1, modulatory calcineurin-interacting protein 1, Myocyte-enriched calcineurin-interacting protein 1, near DSCR proline-rich protein, regulator of calcineurin 1CSP1DSCR1MCIP1RCN1

Gene Symbol

RCAN1

Additional RCAN1 Products

Product Documents for RCAN1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RCAN1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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