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REC8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87145

Novus Biologicals, part of Bio-Techne
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NBP1-87145
NBP1-87145-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for REC8 Antibody

Immunocytochemistry/ Immunofluorescence: REC8 Antibody [NBP1-87145]

Immunocytochemistry/ Immunofluorescence: REC8 Antibody [NBP1-87145]

Immunocytochemistry/Immunofluorescence: REC8 Antibody [NBP1-87145] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: REC8 Antibody [NBP1-87145]

Immunohistochemistry-Paraffin: REC8 Antibody [NBP1-87145]

Immunohistochemistry-Paraffin: REC8 Antibody [NBP1-87145] - Staining of human skin shows very weak positivity in squamous epthelial cells.
Immunohistochemistry-Paraffin: REC8 Antibody [NBP1-87145]

Immunohistochemistry-Paraffin: REC8 Antibody [NBP1-87145]

Immunohistochemistry-Paraffin: REC8 Antibody [NBP1-87145] - Immunohistochemical staining of human testis shows strong nuclear positivity in subsets of cells in seminiferus ducts.

Applications for REC8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: REC8

REC8 encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]

Alternate Names

Cohesin Rec8p, cohesion rec8p, HR21spB, meiotic recombination and sister chromatid cohesion phosphoprotein of therad21p family, meiotic recombination protein REC8 homolog, meiotic recombination protein REC8-like 1, MGC950, REC8 homolog (yeast), REC8L1human homolog of rad21, S. pombe, REC8-like 1, REC8-like 1 (yeast), Rec8p, recombination and sister chromatid cohesion protein homolog

Gene Symbol

REC8

Additional REC8 Products

Product Documents for REC8 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for REC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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