Reg1A Antibody (5F8)

Novus Biologicals, part of Bio-Techne | Catalog # H00005967-M17-100ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 5F8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Reg1A Antibodies »

Product Specifications

Immunogen

REG1A (AAH05350.1, 23 a.a. ~ 122 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYK

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for Reg1A Antibody (5F8)

Western Blot: Reg1A Antibody (5F8) [H00005967-M17-100ug]

Western Blot: Reg1A Antibody (5F8) [H00005967-M17-100ug]

Western Blot: Reg1A Antibody (5F8) [H00005967-M17-100ug] - Detection against Immunogen (36.63 KDa) .
ELISA: Reg1A Antibody (5F8) [H00005967-M17-100ug]

ELISA: Reg1A Antibody (5F8) [H00005967-M17-100ug]

ELISA: Reg1A Antibody (5F8) [H00005967-M17-100ug] - Detection limit for recombinant GST tagged REG1A is 0.3 ng/ml as a capture antibody.

Applications for Reg1A Antibody (5F8)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Reg1A

The Reg family constitutes a subset of the calcium-dependent C-type lectin superfamily. These small, secreted proteins have been implicated in a range of physiological processes including acting as acute phase reactants, lectins, survival/growth factors for insulin-producing pancreatic beta-cells, neural cells, and epithelial cells of the digestive system. Studies also indicate a role for Reg family members in tumor formation and indicate their potential for use as biomarkers of carcinogenesis.

Reg1A, also known as PTP, PSP, and lithostathine, is a member of the Reg family of secreted proteins with a C-type lectin domain. Due to variable glycosylation, pancreatic Reg1A exists as multiple species of 16 - 18 kDa. Reg1A promotes the maintenance and growth of pancreatic islet β-cells and intestinal villi. It is upregulated in pancreatitis and some carcinomas. Reg1A is an antigenic target in autoimmune diabetes. Human Reg1A shares 65% - 68% aa sequence identity with mouse and rat Reg1A.

Long Name

Regenerating Islet-derived 1A

Alternate Names

ICRF, PSP, PTP

Entrez Gene IDs

5967 (Human)

Gene Symbol

REG1A

OMIM

167770 (Human)

UniProt

AAH05350.1 (Human)

Additional Reg1A Products

Product Documents for Reg1A Antibody (5F8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Reg1A Antibody (5F8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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