The Reg family constitutes a subset of the calcium-dependent C-type lectin superfamily. These small, secreted proteins have been implicated in a range of physiological processes including acting as acute phase reactants, lectins, survival/growth factors for insulin-producing pancreatic beta-cells, neural cells, and epithelial cells of the digestive system. Studies also indicate a role for Reg family members in tumor formation and indicate their potential for use as biomarkers of carcinogenesis.

Regenerating protein 2 (Reg2) also known as Lithostathine 2, pancreatic thread protein (PTP2) and pancreatic stone protein 2 (PSP2), is a member of the Reg family of proteins. Reg proteins which are secreted proteins with a C-type lectin domain. Mouse Reg2 is expressed in regenerating islets and normal exocrine pancreas. Reg2 also stimulates the growth of pancreatic beta cells. Mouse Reg2 belongs to the type II subclass of the Reg family and is the only subclass II Reg protein described.

Long Name

Regenerating Islet-derived 2

Alternate Names

regenerating islet-derived 2, RegII

Gene Symbol

REG1B

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Product Specific Notices for Reg2 Antibody (RM0312-5D45) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Reg2 Antibody (RM0312-5D45) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12429PE

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Background: Reg2