Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # MRB 46L

Format

Azide and BSA Free

Concentration

1 mg/ml

View all RELM beta Antibodies »

Product Specifications

Immunogen

Recombinant mouseRELM beta.

Specificity

Recognizes mouse RELM beta. Detects a band of ~10kDa by Western blot. Does not cross-react with human RELM beta.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for RELM beta Antibody (MRB 46L) - Azide and BSA Free

Western Blot: RELM beta Antibody (MRB 46L)Azide and BSA Free [NBP2-80033]

Western Blot: RELM beta Antibody (MRB 46L)Azide and BSA Free [NBP2-80033]

Western Blot: RELM beta Antibody (MRB 46L) - Azide and BSA Free [NBP2-80033] - Analysis using RELM beta (mouse), mAb (MRB 46L) (Prod. No. NBP2-80033) at 1:2'000 dilution.

Applications for RELM beta Antibody (MRB 46L) - Azide and BSA Free

Application
Recommended Usage

ELISA

1:2000 - 1:10000

Western Blot

1:2000 - 1:10000
Application Notes
Western blot: 1:2000-1:10000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 um-filtered solution in PBS, pH 7.4

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RELM beta

RELM beta is a family of resistin-like molecules (RELMs) has been identified in rodents and humans. Resistin is a hormone produced by fat cells. RELMalpha is a secreted protein that has a restricted tissue distribution with highest levels in adipose tissue. Another family member, RELMbeta, is a secreted protein expressed only in the gastrointestinal tract, particularly the colon, in both mouse and human. RELMbeta gene expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation. Resistin and the RELMs share a cysteine composition and other signature features. Thus, the RELMs together with resistin comprise a class of tissue-specific signaling molecules. mRELM-alpha should migrate as a monomer under complete reducing conditions. However, it migrates as dimers, trimers, and even higher order multimers under non-reducing conditions.

Long Name

Resistin-like Molecule beta

Alternate Names

C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 2, CCRG, Colon and small intestine-specific cysteine-rich protein, Colon carcinoma-related gene protein, cysteine-rich secreted A12-alpha-like protein 1, Cysteine-rich secreted protein A12-alpha-like 1, Cysteine-rich secreted protein FIZZ2, FIZZ1, FIZZ2RELM-beta, found in inflammatory zone 1, HXCP2XCP2, RELMb, RELMbeta, resistin like beta, resistin-like beta, RETNL2

Gene Symbol

RETNLB

Additional RELM beta Products

Product Documents for RELM beta Antibody (MRB 46L) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RELM beta Antibody (MRB 46L) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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