Renin Antibody (6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43335

Novus Biologicals, part of Bio-Techne
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NBP3-43335
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Key Product Details

Species Reactivity

Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 6

Concentration

1 mg/ml

View all Renin Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Rat Renin (Uniprot#: P08424; Thr144~Val237)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for Renin Antibody (6)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20 ug/mL

Immunohistochemistry

5-20 ug/mL

Western Blot

0.01-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol.

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Renin

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Alternate Names

Angiotensinogenase, REN

Gene Symbol

REN

Additional Renin Products

Product Documents for Renin Antibody (6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Renin Antibody (6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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