Renin R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90820

Novus Biologicals, part of Bio-Techne
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NBP1-90820
NBP1-90820-25ul
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse, Rat

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Renin R Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NSLSRNNEVDLLFLSELQVLHDISSLLSRHKHLAKDHSPDLYSLELAGLDEIGKRYGEDSEQFRDASKILVDALQKFADDMYSLYGGNAVVELVTVKSFDTSLIRKTRTILEAKQAKNPASPYNLAYKYNFEYSVVFN

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23469216). Rat reactivity reported in scientific literature (PMID: 25250989), Mouse reactivity reported in scientific literature (PMID:25046440).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Renin R Antibody

Western Blot: Renin R Antibody [NBP1-90820]

Western Blot: Renin R Antibody [NBP1-90820]

Western Blot: Renin R Antibody [NBP1-90820] - Analysis in HEK293 cells transfected with control siRNA, target specific siRNA probe #1 and #2. Remaining relative intensity is presented. Loading control: Anti-PPIB.
Immunohistochemistry-Paraffin: Renin R Antibody [NBP1-90820]

Immunohistochemistry-Paraffin: Renin R Antibody [NBP1-90820]

Immunohistochemistry-Paraffin: Renin R Antibody [NBP1-90820] - Staining of human pancreas shows moderate cytoplasmic positivity in islets of Langerhans.
Immunohistochemistry-Paraffin: Renin R Antibody [NBP1-90820]

Immunohistochemistry-Paraffin: Renin R Antibody [NBP1-90820]

Immunohistochemistry-Paraffin: Renin R Antibody [NBP1-90820] - Staining of human cerebellum shows moderate cytoplasmic/ membranous positivity in cells in granular layer
View 3 more images

Applications for Renin R Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. WB, ICC/IF reported in scientific literature (PMID: 25143455).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Renin R

Renin receptor encodes a protein which is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

Long Name

Renin Receptor

Alternate Names

ATP6AP2, ATP6IP2, ATP6M8-9, CAPER, ELDF10, HT028, M8-9, MRXE, MSTP009, N14F, ReninR, XMRE

Gene Symbol

ATP6AP2

Additional Renin R Products

Product Documents for Renin R Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Renin R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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