REXO2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85666

Novus Biologicals, part of Bio-Techne
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NBP1-85666
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all REXO2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YRIIDVSTVKELCRRWYPEEYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKIDEKKRKIIENGENEKTVS

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23435261)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for REXO2 Antibody

Western Blot: REXO2 Antibody [NBP1-85666]

Western Blot: REXO2 Antibody [NBP1-85666]

Western Blot: REXO2 Antibody [NBP1-85666] - Analysis in human cell line U-2 OS.
Immunocytochemistry/ Immunofluorescence: REXO2 Antibody [NBP1-85666]

Immunocytochemistry/ Immunofluorescence: REXO2 Antibody [NBP1-85666]

Immunocytochemistry/Immunofluorescence: REXO2 Antibody [NBP1-85666] - Staining of human cell line U-251 MG shows positivity in mitochondria. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: REXO2 Antibody [NBP1-85666]

Immunohistochemistry-Paraffin: REXO2 Antibody [NBP1-85666]

Immunohistochemistry-Paraffin: REXO2 Antibody [NBP1-85666] - Staining in human parathyroid gland and skeletal muscle tissues using anti-REXO2 antibody. Corresponding REXO2 RNA-seq data are presented for the same tissues.
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Applications for REXO2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: REXO2

REXO2, also known as Oligoribonuclease, mitochondrial, is a 27kDa 237 amino acid protein with a shorter 23kDa 199 isoform. This gene plays a significant role in reparing DNA and is believed to play a role in aiding cells resist UV-C-induced death. REXO2 has been studied in relation to t-cell leukemia, leukemia, tuberculosis and mycobacterium tuberculosis. REXO2 is linked to the ribosome biogenesis in eukaryotes pathway where it interacts with ATG5, MPG, DIS3, UBC and EXOSC10.

Alternate Names

CGI-114, DKFZp566E144, EC 3.1, oligoribonuclease, mitochondrial, REX2, REX2, RNA exonuclease 2 homolog (S. cerevisiae), RFN, RNA exonuclease 2 homolog, SFNMGC111570, Small fragment nuclease, SMFN

Gene Symbol

REXO2

Additional REXO2 Products

Product Documents for REXO2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for REXO2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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