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RFXANK Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13225

Novus Biologicals, part of Bio-Techne
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NBP2-13225
NBP2-13225-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: TQPAEDLIQTQQTPASELGDPEDPGEEAADGSDTVVLSLFPCTPEPVNPEPDASVSSPQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RFXANK Antibody

Immunocytochemistry/ Immunofluorescence: RFXANK Antibody [NBP2-13225]

Immunocytochemistry/ Immunofluorescence: RFXANK Antibody [NBP2-13225]

Immunocytochemistry/Immunofluorescence: RFXANK Antibody [NBP2-13225] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: RFXANK Antibody [NBP2-13225]

Immunohistochemistry-Paraffin: RFXANK Antibody [NBP2-13225]

Immunohistochemistry-Paraffin: RFXANK Antibody [NBP2-13225] - Staining of human kidney shows strong cytoplasmic and nuclear positivity in cells in tubules and strong nuclear staining in cells in glomeruli.

Applications for RFXANK Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RFXANK

RFX-B is the gene responsible for the bare lymphocyte syndrome (BLS) which is characterized by a lack of MHC class II transcription. Subsequently, there is a lack of B and T cell responses to foreign antigens. RFX-B is an MHC class II transcription factor that is defective in BLS.

Alternate Names

ANKRA1Regulatory factor X subunit B, ankyrin repeat-containing regulatory factor X-associated protein, BLS, DNA-binding protein RFXANK, F14150_1, MGC138628, regulatory factor X-associated ankyrin-containing proteinAnkyrin repeat family A protein 1, RFXB, RFX-BRFX-Bdelta4

Gene Symbol

RFXANK

Additional RFXANK Products

Product Documents for RFXANK Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RFXANK Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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