RGS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1029

Novus Biologicals, part of Bio-Techne
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NB100-1029
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all RGS1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-NLLNDLQANSLK corresponding to C-Terminus according to NP_002913.3.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine, Bovine.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for RGS1 Antibody

Western Blot: RGS1 Antibody [NB100-1029]

Western Blot: RGS1 Antibody [NB100-1029]

Western Blot: RGS1 Antibody [NB100-1029] - (1ug/ml) of HepG2 lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Immunohistochemistry-Paraffin: RGS1 Antibody [NB100-1029]

Immunohistochemistry-Paraffin: RGS1 Antibody [NB100-1029]

Immunohistochemistry-Paraffin: RGS1 Antibody [NB100-1029] - staining of paraffin embedded Human Thymus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Immunohistochemistry-Paraffin: RGS1 Antibody [NB100-1029]

Immunohistochemistry-Paraffin: RGS1 Antibody [NB100-1029]

Immunohistochemistry-Paraffin: RGS1 Antibody [NB100-1029] - staining of paraffin embedded Human Small Intestine. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for RGS1 Antibody

Application
Recommended Usage

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Peptide ELISA

Detection limit 1:32000

Western Blot

0.5 - 2 ug/ml
Application Notes
WB: Approx. 25 kDa band observed in HepG2 lysate.
IHC: Paraffin embedded Human Thymus and Small Intestine.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RGS1

This gene encodes a member of the regulator of G protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G proteins by binding to activated, GTP bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G protein heterotrimers, thereby terminating the signal.

Alternate Names

1R20, 1R20Early response protein 1R20, B-cell activation protein BL34, BL34, Early response protein 1R20, HEL-S-87, IER1, IR20, IR20immediate-early response 1, B-cell specific, regulator of G-protein signaling 1, regulator of G-protein signalling 1, RGS1

Entrez Gene IDs

5996 (Human); 50778 (Mouse)

Gene Symbol

RGS1

UniProt

NP_002913 (Human)

Additional RGS1 Products

Product Documents for RGS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RGS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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