RGS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56736

Novus Biologicals, part of Bio-Techne
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NB100-56736
NB100-56736SS
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all RGS2 Antibodies »

Product Specifications

Immunogen

A synthetic peptide within amino acid residues 1-50 of human RGS2 was used as immunogen.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: mouse (86%) and rat (86%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RGS2 Antibody

Western Blot: RGS2 Antibody [NB100-56736]

Western Blot: RGS2 Antibody [NB100-56736]

Western Blot: RGS2 Antibody [NB100-56736] - Western bot analysis of RGS2 in human heart lysate using RGS2 antibody at 2 ug/ml.

Applications for RGS2 Antibody

Application
Recommended Usage

Western Blot

1 - 3 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RGS2

RGSs are a protein family containing a conserved 120 amino acid domain (RGS domain), which bind directly to activated G-alpha subunits (Gai and Gaq) and act as GTPase-activating proteins (GAPs). RGS2 is expressed in thyroid, heart. thyroid, and monocyte-derived DCs. The function of RGS2 as a regulator of Gq is also dependent on regulatory sequences in its amino-terminal domain that direct its localization to the plasma membrane. Recent studies have shown that RGS2 is critical for blood pressure homeostasis, and has been suggested to serve as an effector of the NO-cGMP pathway that promotes vascular relaxation based on studies of aortic rings in vitro.

Alternate Names

Cell growth-inhibiting gene 31 protein, G0 to G1 switch regulatory 8, 24kD, G0/G1 switch regulatory protein 8, G0S8cell growth-inhibiting protein 31, regulator of G-protein signaling 2, regulator of G-protein signaling 2, 24kDa, regulator of G-protein signalling 2, 24kD, regulator of G-protein signalling 2, 24kDa

Entrez Gene IDs

5997 (Human); 19735 (Mouse); 84583 (Rat)

Gene Symbol

RGS2

UniProt

P41220 (Human)

Additional RGS2 Products

Product Documents for RGS2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RGS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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