RICS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92334

Novus Biologicals, part of Bio-Techne
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NBP1-92334
NBP1-92334-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RICS Antibodies »

Product Summary for RICS Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RICS Antibody

Immunocytochemistry/ Immunofluorescence: RICS Antibody [NBP1-92334]

Immunocytochemistry/ Immunofluorescence: RICS Antibody [NBP1-92334]

Immunocytochemistry/Immunofluorescence: RICS Antibody [NBP1-92334] - Staining of human cell line HaCaT shows localization to nucleoplasm, nucleoli fibrillar center & the Golgi apparatus.
Immunohistochemistry-Paraffin: RICS Antibody [NBP1-92334]

Immunohistochemistry-Paraffin: RICS Antibody [NBP1-92334]

Immunohistochemistry-Paraffin: RICS Antibody [NBP1-92334] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry: RICS Antibody [NBP1-92334]

Immunohistochemistry: RICS Antibody [NBP1-92334]

Immunohistochemistry: RICS Antibody [NBP1-92334] - Staining of human colon shows strong cytoplasmic and membrane positivity in glandular cells.
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Applications for RICS Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RICS

RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 (PubMed 12531901)).(supplied by OMIM)

Alternate Names

brain-specific Rho GTP-ase-activating protein, Brain-specific Rho GTPase-activating protein, GAB-associated CDC42, GAB-associated Cdc42/Rac GTPase-activating protein, GC-GAPGTPase regulator interacting with TrkA, GRITp200RhoGAP, KIAA0712p250GAP, MGC1892, rac GTPase activating protein, Rho GTPase activating protein 32, rho GTPase-activating protein 32, Rho/Cdc42/Rac GTPase-activating protein RICS, RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling, RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling, Rho-type GTPase-activating protein 32, RICSPX-RICS

Gene Symbol

ARHGAP32

Additional RICS Products

Product Documents for RICS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RICS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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