RIZ1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-94769

Novus Biologicals, part of Bio-Techne
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NBP2-94769-0.02ml
NBP2-94769-0.1ml
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Key Product Details

Species Reactivity

Validated:

Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RIZ1 Antibodies »

Product Summary for RIZ1 Antibody - BSA Free

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PRDM2 (NP_036363.2). MNQNTTEPVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVKNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEIAAAIEEERASARSKRSSPKSRKGKKKSQENKNKGNKIQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVASQEVPPELA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RIZ1 Antibody - BSA Free

Western Blot: RIZ1 AntibodyBSA Free [NBP2-94769]

Western Blot: RIZ1 AntibodyBSA Free [NBP2-94769]

Western Blot: RIZ1 Antibody [NBP2-94769] - Analysis of extracts of rat heart, using RIZ1 .Exposure time: 90s.
Immunohistochemistry-Paraffin: RIZ1 Antibody - BSA Free [NBP2-94769]

Immunohistochemistry-Paraffin: RIZ1 Antibody - BSA Free [NBP2-94769]

Immunohistochemistry-Paraffin: RIZ1 Antibody [NBP2-94769] - Paraffin-embedded rat testis using RIZ1 .

Applications for RIZ1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RIZ1

RIZ1 (Retinoblastoma proteininteracting zinc finger), also known as PRDM2, is a nuclear protein containing 8 zinc finger motifs. RIZ1 contains a PR domain that may function as protein binding interface in the regulation of chromatin-mediated gene expression. RIZ 1 acts as a tumor suppressor, and RIZ 1 inactivation is common in many types of human cancers, including neuroendocrine, breast, liver, colon, skin, and lymphoid tumors. Similarly, RIZ1 over-expression in breast cancer cells caused cell cycle arrest in G2-M and apoptosis. RIZ1 is highly expressed in human retinoblastoma cells and at low levels in all other human cell lines.

Alternate Names

EC 2.1.1.43, GATA-3 binding protein G3B, GATA-3-binding protein G3B, KMT8PR domain-containing protein 2, Lysine N-methyltransferase 8, MTB-ZFHUMHOXY1, PR domain containing 2, with ZNF domain, PR domain zinc finger protein 2, retinoblastoma protein-binding zinc finger protein, Retinoblastoma protein-interacting zinc finger protein, RIZ1, RIZ2, RIZMTE-binding protein, Zinc finger protein RIZ, zinc-finger DNA-binding protein

Gene Symbol

PRDM2

Additional RIZ1 Products

Product Documents for RIZ1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RIZ1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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