RLBP1L1 Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29652

Novus Biologicals, part of Bio-Techne
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NBP2-29652
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Key Product Details

Species Reactivity

Validated:

Rat

Predicted:

Human (100%), Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RLBP1L1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # A6JFQ6

Reactivity Notes

It is anticipated that the antibody will also work in human and mouse as there is 100% homology in these species with the amino acid sequence used as antigen.

Specificity

Specific for endogenous levels of the ~35 kDa clavesin 1/2 protein doublet. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are clavesin 1 and 2, respectively.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RLBP1L1 Antibody - Azide and BSA Free

Western Blot: RLBP1L1 AntibodyAzide and BSA Free [NBP2-29652]

Western Blot: RLBP1L1 AntibodyAzide and BSA Free [NBP2-29652]

Western Blot: RLBP1L1 Antibody [NBP2-29652] - rat hippocampal homogenate showing specific immunolabeling of the ~ 35k clavesin protein.

Applications for RLBP1L1 Antibody - Azide and BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS and 50% Glycerol

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RLBP1L1

Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009). Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008).

Alternate Names

Cellular retinaldehyde-binding protein-like, clavesin 1, clavesin-1, CRALBPLC6orf212L, FLJ37248, MGC34646, retinaldehyde binding protein 1-like 1, Retinaldehyde-binding protein 1-like 1, RLBP1L1

Entrez Gene IDs

366311 (Rat)

Gene Symbol

CLVS1

UniProt

A6JFQ6 (Rat)

Additional RLBP1L1 Products

Product Documents for RLBP1L1 Antibody - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RLBP1L1 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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