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RND3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98843

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human RND3.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for RND3 Antibody

Western Blot: RND3 Antibody [NBP2-98843]

Western Blot: RND3 Antibody [NBP2-98843]

Western Blot: RND3 Antibody [NBP2-98843] - Anti-RND3 rabbit polyclonal antibody at 1:500 dilution. Lane A: NCI-H460 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 27 kDa. Observed band size: 30 kDa

Applications for RND3 Antibody

Application
Recommended Usage

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RND3

RND3 is a gene that codes for a protein that binds GTP but is resistant to Rho-specific GTPase-activating proteins as well as lacks certain GTPase activities, and is 244 amino acids long and weighs approximately 27 kDa. Current studies are being done on several diseases and disorders relating to this gene including colon, gastric, lung and prostate cancers, glioblastoma, hypoxia, prostatitis, melanoma, and carcinoma. RND3 has also been shown to have interactions with SFN, ARHGAP5, PLXNB1, ROCK1, and UBXN11 in pathways such as the cytoskeletal signaling and selected targets of CREB1 and p53 pathways.

Long Name

Rho family GTPase 3

Alternate Names

ARHE, MemB, Rho8

Gene Symbol

RND3

Additional RND3 Products

Product Documents for RND3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RND3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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