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RNF40 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-53086

Novus Biologicals, part of Bio-Techne
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NBP1-53086

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

Product Summary for RNF40 Antibody

Immunogen

Synthetic peptides corresponding to RNF40 (ring finger protein 40). The peptide sequence was selected from the C terminal of RNF40. Peptide sequence KLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELT. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

67 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for RNF40 Antibody

Western Blot: RNF40 Antibody [NBP1-53086]

Western Blot: RNF40 Antibody [NBP1-53086]

Western Blot: RNF40 Antibody [NBP1-53086] - Antibody Titration: 1.25ug/ml Positive Control: 293T cell lysate
Immunohistochemistry: RNF40 Antibody [NBP1-53086]

Immunohistochemistry: RNF40 Antibody [NBP1-53086]

Immunohistochemistry: RNF40 Antibody [NBP1-53086] - SampleType : Adult mouse cerebellum (l0x) section Dilution : 1: 100 Secondary Antibody : Donkey Anti-rabbit (568 nm) Secondary Antibody Dilution : 1: 500 Color/Signal Descriptions : RNF40: Red DAPI: Blue Gene Name : RNF40 Submitted by : Anonymous
Immunohistochemistry: RNF40 Antibody [NBP1-53086]

Immunohistochemistry: RNF40 Antibody [NBP1-53086]

Immunohistochemistry: RNF40 Antibody [NBP1-53086] - Human Muscle

Applications for RNF40 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RNF40

RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

Alternate Names

95 kDa retinoblastoma-associated protein, BRE1-B, BRE1BMGC13051, EC 6.3.2,95 kDa retinoblastoma protein binding protein, EC 6.3.2.-, KIAA0661BRE1 E3 ubiquitin ligase homolog B, Rb-associated protein, RBP95E3 ubiquitin-protein ligase BRE1B, ring finger protein 40DKFZp686K191, STARING

Gene Symbol

RNF40

UniProt

Additional RNF40 Products

Product Documents for RNF40 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RNF40 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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