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RNF6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84107

Novus Biologicals, part of Bio-Techne
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NBP1-84107
NBP1-84107-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TLGRLRNGIGGAAGIPRANASRTNFSSHTNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEPIRLRST

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RNF6 Antibody

Immunocytochemistry/ Immunofluorescence: RNF6 Antibody [NBP1-84107]

Immunocytochemistry/ Immunofluorescence: RNF6 Antibody [NBP1-84107]

Immunocytochemistry/Immunofluorescence: RNF6 Antibody [NBP1-84107] - Immunofluorescent staining of human cell line A-431 shows localization to nuclear membrane & vesicles.
Immunohistochemistry-Paraffin: RNF6 Antibody [NBP1-84107]

Immunohistochemistry-Paraffin: RNF6 Antibody [NBP1-84107]

Immunohistochemistry-Paraffin: RNF6 Antibody [NBP1-84107] - Staining of human bone marrow shows strong nuclear positivity in bone marrow poietic cells.

Applications for RNF6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RNF6

RNF6 is encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.

Alternate Names

DKFZp686P0776, E3 ubiquitin-protein ligase RNF6, EC 6.3.2.-, ring finger protein (C3H2C3 type) 6, RING-H2 protein RNF-6, SPG2

Gene Symbol

RNF6

Additional RNF6 Products

Product Documents for RNF6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RNF6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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