ROR alpha/NR1F1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25112

Novus Biologicals, part of Bio-Techne
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NBP3-25112
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ROR alpha/NR1F1 Antibodies »

Product Summary for ROR alpha/NR1F1 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein ROR alpha/NR1F1 using the following amino acid sequence: VQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ROR alpha/NR1F1 Antibody

ROR alpha/NR1F1 Antibody Western Blot: ROR alpha/NR1F1 Antibody [NBP3-25112]

Western Blot: ROR alpha/NR1F1 Antibody [NBP3-25112]

Analysis in human cell line RT-4.
ROR alpha/NR1F1 Antibody Immunocytochemistry/Immunofluorescence: ROR alpha/NR1F1 Antibody [NBP3-25112]

Immunocytochemistry/Immunofluorescence: ROR alpha/NR1F1 Antibody [NBP3-25112]

Staining of human cell line U2OS shows localization to nucleoli.

Applications for ROR alpha/NR1F1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml

Western Blot

0.04-0.4 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ROR alpha/NR1F1

Retinoid related orphan receptor alpha (ROR alpha) is a NR1 Thyroid Hormone Like Receptor. To date, ROR alpha, beta, and gamma subtypes have been discovered. ROR alpha has been shown to affect the development of the central nervous system. Deletion of ROR alpha in mice causes severe impairment in the differentiation of cerebellar Purkinje neurons and results in the "staggerer" phenotype. ROR alpha has been suggested as a potential target in the treatment of chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis.

Long Name

Retinoic Acid-Related Orphan Receptor alpha

Alternate Names

NR1F1, RORA, RZRA

Gene Symbol

RORA

Additional ROR alpha/NR1F1 Products

Product Documents for ROR alpha/NR1F1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ROR alpha/NR1F1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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