Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # RORC/8017R

Format

Azide and BSA Free

Concentration

1 mg/ml

View all ROR gamma/RORC/NR1F3 Antibodies »

Product Specifications

Immunogen

Recombinant full-length human ROR gamma/RORC/NR1F3 protein

Localization

Nucleus.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Description

Positive Controls: MOLT4 cells. Human lymphocytes. Human liver or skeletal muscle tissue.

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for ROR gamma/RORC/NR1F3 Antibody (RORC/8017R) - Azide and BSA Free

ROR gamma/RORC/NR1F3 Antibody (RORC/8017R) - Azide and BSA Free

ROR gamma/RORC/NR1F3 Antibody (RORC/8017R)

Formalin-fixed, paraffin-embedded human kidney stained with ROR gamma/RORC/NR1F3 antibody (RORC/8017R). HIER: Tris/EDTA, pH9.0, 45min. Secondary: HRP-polymer, 30min. DAB, 5min.
ROR gamma/RORC/NR1F3 Antibody (RORC/8017R) - Azide and BSA Free

ROR gamma/RORC/NR1F3 Antibody (RORC/8017R)

Formalin-fixed, paraffin-embedded human kidney stained with ROR gamma/RORC/NR1F3 antibody (RORC/8017R). Inset: PBS instead of primary antibody; secondary only negative control.

Applications for ROR gamma/RORC/NR1F3 Antibody (RORC/8017R) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes. at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.

Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: ROR gamma/RORC/NR1F3

ROR gamma/RORC/NR1F3, aka RAR Orphan Receptor gamma, is a Nuclear Receptor 1 Thyroid Hormone-Like receptor containing a short A-T rich sequence follow by a single core motif half-site 5'-AGGTCA-3'. RORC is a key regulator of thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. NR1F3 regulates intrinsic transcriptional functions. Unlike other major nuclear receptors, RORC binds as a monomer to hormone response elements and is documented in mouse thymus, adipose, bone, skeletal muscle, liver, kidney, and human skeletal muscle. An N-terminal isoform of ROR gamma, ROR gamma T, inhibits Fas ligand expression and cytokine secretion in immature thymocytes.

Long Name

Retinoic Acid-Related Orphan Receptor gamma

Alternate Names

NR1F3, RORC, RZRG

Gene Symbol

RORC

Additional ROR gamma/RORC/NR1F3 Products

Product Documents for ROR gamma/RORC/NR1F3 Antibody (RORC/8017R) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ROR gamma/RORC/NR1F3 Antibody (RORC/8017R) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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