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ROR1 Antibody (zilovertamab) - Humanized

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28157

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-28157-100ug
NBP3-28157-50ug

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # zilovertamab

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

ROR1

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.14 kDa.

Also known as 'zilovertamab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ROR1 Antibody (zilovertamab) - Humanized

ROR1 Antibody (zilovertamab) - Humanized

ELISA: ROR1 Antibody (zilovertamab) - Humanized[NBP3-28157] -

Immobilized human ROR1 His at 2 ug/mL can bind ROR1 Antibody (zilovertamab) - Humanized, EC50=0.00283 ug/mL.
ROR1 Antibody (zilovertamab) - Humanized

Functional: ROR1 Antibody (zilovertamab) - Humanized[NBP3-28157] -

zilovertamab by Human ROR1 HEK293T cells increased with the increase of antibody concentration, and the Internalization Rate (%) reached 72%.
ROR1 Antibody (zilovertamab) - Humanized

Flow Cytometry: ROR1 Antibody (zilovertamab) - Humanized[NBP3-28157] -

A549 cells were stained with ROR1 Antibody (zilovertamab) - Humanized and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.002776 ug/ml.

Applications for ROR1 Antibody (zilovertamab) - Humanized

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: ROR1

ROR1 is encoded by this gene is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Long Name

Receptor Tyrosine Kinase-like Orphan Receptor 1

Alternate Names

NTRKR1

Gene Symbol

ROR1

UniProt

Additional ROR1 Products

Product Documents for ROR1 Antibody (zilovertamab) - Humanized

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ROR1 Antibody (zilovertamab) - Humanized

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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