RP105/CD180 Antibody (105)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90611

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 105

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RP105/CD180 Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse RP105/CD180 (Accession#: NP_032559.2; Met1-Ser626).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for RP105/CD180 Antibody (105)

Immunohistochemistry-Paraffin: RP105/CD180 Antibody (105) [NBP2-90611]

Immunohistochemistry-Paraffin: RP105/CD180 Antibody (105) [NBP2-90611]

Immunohistochemistry-Paraffin: RP105/CD180 Antibody (105) [NBP2-90611] - Immunochemical staining of mouse RP105/CD180 in mouse thymus with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: RP105/CD180 Antibody (105) [NBP2-90611]

Immunohistochemistry-Paraffin: RP105/CD180 Antibody (105) [NBP2-90611]

Immunohistochemistry-Paraffin: RP105/CD180 Antibody (105) [NBP2-90611] - Immunochemical staining of mouse RP105/CD180 in mouse spleen with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).

Applications for RP105/CD180 Antibody (105)

Application
Recommended Usage

ELISA

1:5000-1:10000

Immunohistochemistry-Paraffin

1:50-1:200

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RP105/CD180

CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.

Alternate Names

CD180, Ly64

Gene Symbol

CD180

Additional RP105/CD180 Products

Product Documents for RP105/CD180 Antibody (105)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RP105/CD180 Antibody (105)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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