RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62228

Clone G28-8 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Functional, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # G28-8

Format

Azide and BSA Free

Concentration

1 mg/ml

View all RP105/CD180 Antibodies »

Product Specifications

Immunogen

Human tonsillar B cells

Specificity

The mouse monoclonal antibody G28-8 recognizes an extracellular epitope of RP105/CD180, a 95-105 kDa TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Endotoxin Level

Endotoxin level is less than 0.01 EU/ug of the protein

Theoretical MW

105 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free

Flow (Cell Surface): RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free [NBP2-62228]

Flow (Cell Surface): RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free [NBP2-62228]

Flow (Cell Surface): RP105/CD180 Antibody (G28-8) - Low Endotoxin [NBP2-62228] - Surface staining of human peripheral blood cells with anti-CD180 (G28-8) APC.
Flow (Cell Surface): RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free [NBP2-62228]

Flow (Cell Surface): RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free [NBP2-62228]

Flow (Cell Surface): RP105/CD180 Antibody (G28-8) - Low Endotoxin [NBP2-62228] - Surface staining of human peripheral blood cells with anti-CD180 (G28-8) PE.

Applications for RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

2 ug/ml

Immunoprecipitation

1:10-1:500

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4), 0.2 um filter sterilized

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: RP105/CD180

CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.

Alternate Names

CD180, Ly64

Gene Symbol

CD180

Additional RP105/CD180 Products

Product Documents for RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RP105/CD180 Antibody (G28-8) - Low Endotoxin - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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