RPSA Antibody (MLuC5)

Novus Biologicals, part of Bio-Techne | Catalog # NB200-631

Novus Biologicals, part of Bio-Techne
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NB200-631
NB200-631-100ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgM Clone # MLuC5

Concentration

0.2 mg/ml

View all RPSA Antibodies »

Product Specifications

Immunogen

Small cell lung carcinoma N592 live cells

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 21320497).

Localization

Cell membrane with some cytoplasmic.

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Scientific Data Images for RPSA Antibody (MLuC5)

Western Blot: RPSA Antibody (MLuC5) [NB200-631]

Western Blot: RPSA Antibody (MLuC5) [NB200-631]

Western Blot: RPSA Antibody (MLuC5) [NB200-631] - Analysis of 25 ug of HepG2 (lane 1) and Hela (lane 2) cell lysates.
Immunocytochemistry/ Immunofluorescence: RPSA Antibody (MLuC5) [NB200-631]

Immunocytochemistry/ Immunofluorescence: RPSA Antibody (MLuC5) [NB200-631]

Immunocytochemistry/Immunofluorescence: RPSA Antibody (MLuC5) [NB200-631] - Analysis of Laminin Receptor (green) showing staining in the membrane of MCF-7 cells (right) compared to a negative control without primary antibody (left).
Immunohistochemistry-Paraffin: RPSA Antibody (MLuC5) [NB200-631]

Immunohistochemistry-Paraffin: RPSA Antibody (MLuC5) [NB200-631]

Immunohistochemistry-Paraffin: RPSA Antibody (MLuC5) [NB200-631] - Human breast carcinoma stained with Laminin Receptor antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane with some cytoplasmic staining of tumor cells.
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Applications for RPSA Antibody (MLuC5)

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000

Immunocytochemistry/ Immunofluorescence

1:10 - 1:200

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

4 - 8 ug/mL

Western Blot

1:10 - 1:200

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

PBS (pH 7.4) and 0.2% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: RPSA

Laminin, one of the major glycoproteins of basement membrane, displays multiple biological activities which are mediated through its interaction with specific cell membrane receptors. Overexpression of laminin receptor is reportedly an independent prognostic factor in breast cancer and correlates with the dissemination of the tumor cells in bone marrow. Laminin receptor appears to play an important role in tumor invasion and metastasis.

Alternate Names

37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 37LRPNEM/1CHD4, 67 kDa laminin receptor, 67kD, ribosomal protein SA, 67LR, Colon carcinoma laminin-binding protein, LAMBR37 kDa laminin receptor, laminin binding protein, Laminin receptor 1, laminin receptor 1 (67kD, ribosomal protein SA), Laminin-binding protein precursor p40, lamR, LAMR 1, LAMR140S ribosomal protein SA, LBP, LBP/p40, LRP, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, p40, ribosomal protein SA

Entrez Gene IDs

3921 (Human)

Gene Symbol

RPSA

UniProt

P08865 (Human)

Additional RPSA Products

Product Documents for RPSA Antibody (MLuC5)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RPSA Antibody (MLuC5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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