RRP1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81533

Novus Biologicals, part of Bio-Techne
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NBP1-81533-25ul
NBP1-81533
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RRP1B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SISQLSFAEDISADEDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTG

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23604122)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RRP1B Antibody

Western Blot: RRP1B Antibody [NBP1-81533]

Western Blot: RRP1B Antibody [NBP1-81533]

Western Blot: RRP1B Antibody [NBP1-81533] - Analysis in U2OS cells transfected with control siRNA, target specific siRNA probe #1 and #2. Remaining relative intensity is presented.
Immunocytochemistry/ Immunofluorescence: RRP1B Antibody [NBP1-81533]

Immunocytochemistry/ Immunofluorescence: RRP1B Antibody [NBP1-81533]

Immunocytochemistry/Immunofluorescence: RRP1B Antibody [NBP1-81533] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoli.
Immunohistochemistry-Paraffin: RRP1B Antibody [NBP1-81533]

Immunohistochemistry-Paraffin: RRP1B Antibody [NBP1-81533]

Immunohistochemistry-Paraffin: RRP1B Antibody [NBP1-81533] - Staining of human tonsil shows moderate to strong nuclear positivity in non-germinal center cells.
View 3 more images

Applications for RRP1B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RRP1B

The RRP1B gene enocdes a ribosomal RNA processing protein 1 homolog B that in isoform 1 is 758 amino acids and 84kDA and in isoform 2 is 740 amino acids long at 82 kDA. RRP1B is characterized by its interactions with genes ESR2, LSM1, LUC7L2, LUC7L3, and C7orf55-LUC7L2. It has been researched regarding its role in various diseases such as breast cancer and cancer progression in terms of metastasis efficiency.

Alternate Names

Nnp1, ribosomal RNA processing 1 homolog B (S. cerevisiae), RRP1

Gene Symbol

RRP1B

Additional RRP1B Products

Product Documents for RRP1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RRP1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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