RSK4 Antibody (SR2252)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22070

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22070-100ul
NBP3-22070-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2252

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RSK4 Antibodies »

Product Summary for RSK4 Antibody (SR2252)

Immunogen

A synthesized peptide derived from human RSK4 (Uniprot #: Q9UK32)

Specificity

Detects endogenous levels of total RSK4

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RSK4 Antibody (SR2252)

Western Blot: RSK4 Antibody (SR2252) [NBP3-22070] -

Western Blot: RSK4 Antibody (SR2252) [NBP3-22070] - Western blot analysis using NBP3-22070 in SH-SY5Y cell lysate.

Applications for RSK4 Antibody (SR2252)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RSK4

RSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3).

Long Name

Ribosomal Protein S6 Kinase IV

Alternate Names

RPS6KA6

Gene Symbol

RPS6KA6

Additional RSK4 Products

Product Documents for RSK4 Antibody (SR2252)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RSK4 Antibody (SR2252)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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