RTN3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88870

Novus Biologicals, part of Bio-Techne
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NBP1-88870
NBP1-88870-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RTN3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RTN3 Antibody

Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870]

Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870]

Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870]

Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870]

Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870] - Staining of human colon shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870]

Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870]

Immunohistochemistry-Paraffin: RTN3 Antibody [NBP1-88870] - Staining of human liver shows no positivity in hepatocytes as expected.
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Applications for RTN3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RTN3

May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

Alternate Names

ASYIPASY interacting protein, HAP, isoforme III, isoforme VI, Neuroendocrine-specific protein-like 2, Neuroendocrine-specific protein-like II, NSPL2NSP-like protein II, NSPLIIhomolog of ASY protein, NSP-like protein 2, reticulon 3, reticulon-3, RTN3-A1

Gene Symbol

RTN3

Additional RTN3 Products

Product Documents for RTN3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for RTN3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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