RXR beta/NR2B2 Antibody (147)

Novus Biologicals, part of Bio-Techne | Catalog # NB300-311

Novus Biologicals, part of Bio-Techne
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NB300-311
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 147

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RXR beta/NR2B2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH. Accession # P28702

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Localization

Cytoplasmic (isoform beta 4) and Nuclear (isoforms beta 1 and beta 2).

Specificity

Specific for endogenous levels of the ~48 kDa RXR beta/NR2B2 protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RXR beta/NR2B2 Antibody (147)

Western Blot: RXR beta/NR2B2 Antibody (147) [NB300-311]

Applications for RXR beta/NR2B2 Antibody (147)

Application
Recommended Usage

Western Blot

1:1000
Application Notes
This antibody has been tested in Western blot, detecting a band ~48 kDa.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RXR beta/NR2B2

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR0, 1 and g), preferentially bind 9- is-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Long Name

Retinoid X Receptor, beta

Alternate Names

H-2RIIBP, NR2B2, RXRB

Entrez Gene IDs

218772 (Mouse)

Gene Symbol

RXRB

UniProt

P28702 (Human)

Additional RXR beta/NR2B2 Products

Product Documents for RXR beta/NR2B2 Antibody (147)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RXR beta/NR2B2 Antibody (147)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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