RXR beta/NR2B2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25118

Novus Biologicals, part of Bio-Techne
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NBP3-25118
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RXR beta/NR2B2 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein RXR beta/NR2B2 using the following amino acid sequence: VAGGEQQTPEPEPGEAGRDGMGDSGRDSRSP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RXR beta/NR2B2 Antibody

RXR beta/NR2B2 Antibody Immunocytochemistry/Immunofluorescence: RXR beta/NR2B2 Antibody [NBP3-25118]

Immunocytochemistry/Immunofluorescence: RXR beta/NR2B2 Antibody [NBP3-25118]

Staining of human cell line U2OS shows localization to nucleoplasm.

Applications for RXR beta/NR2B2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RXR beta/NR2B2

Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

Long Name

Retinoid X Receptor, beta

Alternate Names

H-2RIIBP, NR2B2, RXRB

Gene Symbol

RXRB

Additional RXR beta/NR2B2 Products

Product Documents for RXR beta/NR2B2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RXR beta/NR2B2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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