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S100A7/Psoriasin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87205

Novus Biologicals, part of Bio-Techne
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NBP1-87205
NBP1-87205-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EKPSLLTMMKENFPNFLSACDKKGTNYLADVFEKKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for S100A7/Psoriasin Antibody

Immunohistochemistry: S100A7/Psoriasin Antibody [NBP1-87205]

Immunohistochemistry: S100A7/Psoriasin Antibody [NBP1-87205]

Immunohistochemistry: S100A7/Psoriasin Antibody [NBP1-87205] - Zn-binding protein immunohistochemical staining in OPSCC. Examples from nanozoomer digitized scans (20X magnification) of low, moderate and high cytoplasmic staining of OPSCC tumor tissue for the Zn-binding proteins AZGP1, Lipocalin-1, serum Albumin, S100A7, S100A8 and S100A9. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41598-019-53268-1), licensed under a CC-BY license.
Immunohistochemistry-Paraffin: S100A7/Psoriasin Antibody [NBP1-87205]

Immunohistochemistry-Paraffin: S100A7/Psoriasin Antibody [NBP1-87205]

Immunohistochemistry-Paraffin: S100A7/Psoriasin Antibody [NBP1-87205] - Staining of human skin shows strong nuclear and cytoplasmic positivity in a subset of epidermal cells.
S100A7/Psoriasin Antibody

Immunohistochemistry: S100A7/Psoriasin Antibody [NBP1-87205] -

Immunohistochemistry: S100A7/Psoriasin Antibody [NBP1-87205] - Zn-binding protein immunohistochemical staining in OPSCC. Examples from nanozoomer digitized scans (20X magnification) of low, moderate & high cytoplasmic staining of OPSCC tumor tissue for the Zn-binding proteins AZGP1, Lipocalin-1, serum Albumin, S100A7, S100A8 & S100A9. Image collected & cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31740720), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Applications for S100A7/Psoriasin Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:500-1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: S100A7

Psoriasin / S100A7 is encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.

Long Name

S100 Calcium Binding Protein A7

Alternate Names

PSOR1

Entrez Gene IDs

6278 (Human)

Gene Symbol

S100A7

UniProt

Additional S100A7 Products

Product Documents for S100A7/Psoriasin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for S100A7/Psoriasin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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