S1P1/EDG-1 Antibody (MM0045-21L9) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-93513JF525

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB110-93513AF350

Alexa Fluor 405

NB110-93513AF405

Alexa Fluor 488

NB110-93513AF488

Alexa Fluor 532

NB110-93513AF532

Alexa Fluor 594

NB110-93513AF594

Alexa Fluor 647

NB110-93513AF647

Alexa Fluor 700

NB110-93513AF700

Alexa Fluor 750

NB110-93513AF750

Allophycocyanin

NB110-93513APC

Allophycocyanin/Cy7

NB110-93513APCCY7

Biotin

NB110-93513B

CoraFluor 1

NB110-93513CL1

DyLight 350

NB110-93513UV

DyLight 405

NB110-93513V

DyLight 488

NB110-93513G

DyLight 550

NB110-93513R

DyLight 594

NB110-93513DL594

DyLight 650

NB110-93513C

DyLight 680

NB110-93513FR

DyLight 755

NB110-93513IR

FITC

NB110-93513F

HRP

NB110-93513H

Janelia Fluor 549

NB110-93513JF549

Janelia Fluor 585

NB110-93513JF585

Janelia Fluor 635

NB110-93513JF635

Janelia Fluor 646

NB110-93513JF646

Janelia Fluor 669

NB110-93513JF669

mFluor Violet 450 SE

NB110-93513MFV450

mFluor Violet 500 SE

NB110-93513MFV500

mFluor Violet 610 SE

NB110-93513MFV610

PE

NB110-93513PE

PE/Atto594

NB110-93513PEATT594

PE/Cy5.5

NB110-93513PECY55

PE/Cy7

NB110-93513PECY7

PerCP

NB110-93513PCP

Forumulation

Catalog #

Azide and BSA Free

NB110-93513

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Janelia Fluor 525

Antibody Source

Monoclonal Mouse IgG₁ Clone # MM0045-21L9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all S1P1/EDG-1 Antibodies »

Product Summary for S1P1/EDG-1 Antibody (MM0045-21L9) [Janelia Fluor® 525]

Immunogen

Human recombinant S1P1/EDG-1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for S1P1/EDG-1 Antibody (MM0045-21L9) [Janelia Fluor® 525]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: S1P1/EDG-1

EBP 50 [ERM (ezrin-radixin-moesin) binding phosphoprotein of 50 kDa] is a PDZ containing protein that is involved in the linkage of integral membrane proteins to the cytoskeleton. EBP50 contains two tandem PDZ domains followed by a carboxy-terminal sequence that binds to members of the ERM family of membrane-cytoskeleton adaptors. The PDZ domains within EBP50 bind to the carboxy termini of such target proteins as beta2 adrenergic receptor, platelet-derived growth factor receptor (PDGFR), and the cystic fibrosis conductance regulator (CFTR). The PDZ domains are also believed to be involved in the oligomerization of EBP 50 to form multiprotein complexes which helps to facilitate the formation of functional signalling complexes. EBP 50 has been shown to link integral membrane proteins to the cytoskeleton by binding to members of the ERM family of proteins, which bind to F-actin. Through these interactions, EBP 50 is implicated in the localization of interactive groups of proteins into subcellular domains and in the regulation of activity of those interacting proteins. Immunohistochemical studies have shown that EBP 50 is found exclusively at the apical membranes of epithelial cells.

Long Name

Endothelial Differentiation Gene 1

Alternate Names

CD363, EDG1, S1PR1

Gene Symbol

S1PR1

Additional S1P1/EDG-1 Products

Product Documents for S1P1/EDG-1 Antibody (MM0045-21L9) [Janelia Fluor® 525]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for S1P1/EDG-1 Antibody (MM0045-21L9) [Janelia Fluor® 525]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
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