S1P1/EDG-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27291

Novus Biologicals, part of Bio-Techne
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NBP2-27291
NBP2-27291SS
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all S1P1/EDG-1 Antibodies »

Product Summary for S1P1/EDG-1 Antibody

Immunogen

A portion of amino acids 1-60 of human S1P1/EDG-1 was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 83% homologous in bovine, 81% in mouse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for S1P1/EDG-1 Antibody

Immunohistochemistry-Paraffin: S1P1/EDG-1 Antibody [NBP2-27291]

Immunohistochemistry-Paraffin: S1P1/EDG-1 Antibody [NBP2-27291]

Immunohistochemistry-Paraffin: S1P1/EDG-1 Antibody [NBP2-27291] - Analysis of S1P1/EDG-1 in FFPE human brain tissue using an isotype control (top left) and this antibody (bottom left, right)

Applications for S1P1/EDG-1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: S1P1/EDG-1

S1PR1 (Sphingosine-1-phosphate receptor 1) is also known as Endothelial differentiation G-protein coupled receptor 1. It is the receptor for, and binds to, the lipid signaling molecule Sphingosine 1-phosphate (S1P) with high affinity and specificity, and is suggested to be involved in regulatory processes of differentiation of endothelial cells and cell-cell adhesion. S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissuesThis inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. It seems to be coupled to the G (i) subclass of heteromeric G proteins.

Long Name

Endothelial Differentiation Gene 1

Alternate Names

CD363, EDG1, S1PR1

Gene Symbol

S1PR1

UniProt

P21453

Additional S1P1/EDG-1 Products

Product Documents for S1P1/EDG-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for S1P1/EDG-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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