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S1P3/EDG-3 Antibody (SR1706)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22313

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-22313-100ul
NBP3-22313-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1706

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for S1P3/EDG-3 Antibody (SR1706)

Immunogen

A synthesized peptide derived from human S1P3/EDG-3 (Uniprot #: Q99500)

Specificity

Detects endogenous levels of total S1P3/EDG-3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for S1P3/EDG-3 Antibody (SR1706)

Western Blot: S1P3/EDG-3 Antibody (SR1706) [NBP3-22313] -

Western Blot: S1P3/EDG-3 Antibody (SR1706) [NBP3-22313] - Western blot analysis using NBP3-22313 in HepG2 cell lysate.

Applications for S1P3/EDG-3 Antibody (SR1706)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: S1P3/EDG-3

EDG3, a Lysophospholipid/Lysosphingolipid Receptor, binds the vasoconstrictor sphingosine-1-phosphate and activates transcription of serum response element-driven reporter genes. EDG3 may regulate angiogenesis and vascular endothelial cell functions. EDG3 has been reported in all tissues, with highest levels in heart, placenta, kidney, and liver. ESTs have been isolated from placenta and germ cell tumor libraries.

Long Name

Endothelial Differentiation Gene 3

Alternate Names

EDG3, LPB3, S1PR3

Gene Symbol

S1PR3

Additional S1P3/EDG-3 Products

Product Documents for S1P3/EDG-3 Antibody (SR1706)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for S1P3/EDG-3 Antibody (SR1706)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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