S1P3/EDG-3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24762

Novus Biologicals, part of Bio-Techne
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NBP2-24762
NBP2-24762SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all S1P3/EDG-3 Antibodies »

Product Summary for S1P3/EDG-3 Antibody

Immunogen

A portion of amino acids 300-350 of human Sphingolipid Receptor Edg3/S1P3 was used as the immunogen.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for S1P3/EDG-3 Antibody

Western Blot: S1P3/EDG-3 Antibody [NBP2-24762]

Western Blot: S1P3/EDG-3 Antibody [NBP2-24762]

Western Blot: S1P3/EDG-3 Antibody [NBP2-24762] - Human neuroblastoma with various drugs and control. Image from verified customer review.
Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NBP2-24762]

Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NBP2-24762]

Immunohistochemistry-Paraffin: S1P3/EDG-3 Antibody [NBP2-24762] - Human liver tissue using an isotype control (top left) and NBP2-24762 (bottom left, right) at 5 ug/ml.
Western Blot: S1P3/EDG-3 Antibody [NBP2-24762]

Western Blot: S1P3/EDG-3 Antibody [NBP2-24762]

Western Blot: S1P3/EDG-3 Antibody [NBP2-24762] - Sphingolipid Receptor Edg3/S1P3 in kidney lysate. Lane 1 shows pre-immune sera. Lanes 2 and 3 show NBP2-24762 tested on human kidney (2 ug/ml) and mouse kidney (1 ug/ml) lysate.

Applications for S1P3/EDG-3 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1.0-2.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: S1P3/EDG-3

EDG3, a Lysophospholipid/Lysosphingolipid Receptor, binds the vasoconstrictor sphingosine-1-phosphate and activates transcription of serum response element-driven reporter genes. EDG3 may regulate angiogenesis and vascular endothelial cell functions. EDG3 has been reported in all tissues, with highest levels in heart, placenta, kidney, and liver. ESTs have been isolated from placenta and germ cell tumor libraries.

Long Name

Endothelial Differentiation Gene 3

Alternate Names

EDG3, LPB3, S1PR3

Gene Symbol

S1PR3

UniProt

Q99500 (Human)

Additional S1P3/EDG-3 Products

Product Documents for S1P3/EDG-3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for S1P3/EDG-3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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