S5a/Angiocidin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19951

Novus Biologicals, part of Bio-Techne
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NBP2-19951
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (99%), Canine (99%), Chicken (97%), Mouse (99%), Porcine (100%), Primate (100%), Rabbit (98%), Rat (99%), Rhesus Macaque (100%), Sheep (100%), Xenopus (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all S5a/Angiocidin Antibodies »

Product Summary for S5a/Angiocidin Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human S5a/Angiocidin. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (94%), Chimpanzee (100%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for S5a/Angiocidin Antibody

Western Blot: S5a/Angiocidin Antibody [NBP2-19951]

Western Blot: S5a/Angiocidin Antibody [NBP2-19951]

Western Blot: Proteasome 19S S5A Antibody [NBP2-19951] - Sample (30 ug of whole cell lysate) A: A549 B: Hela C: Hep G2 D: HCT116 10% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: S5a/Angiocidin Antibody [NBP2-19951]

Immunocytochemistry/ Immunofluorescence: S5a/Angiocidin Antibody [NBP2-19951]

Immunocytochemistry/Immunofluorescence: Proteasome 19S S5A Antibody [NBP2-19951] - SK-N-SH cells. Green: PSMD4 protein stained by PSMD4. Blue: Hoechst 33342 staining.

Applications for S5a/Angiocidin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: S5a/Angiocidin

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq]

Long Name

26S Proteasome Regulatory Subunit S5a

Alternate Names

Angiocidin, ASF, Macropain, Mcb1, PSMD4, pUB-R5, Rpn10, S5a

Gene Symbol

PSMD4

UniProt

P55036 (Human)

Additional S5a/Angiocidin Products

Product Documents for S5a/Angiocidin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for S5a/Angiocidin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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