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SAMHD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31432

Novus Biologicals, part of Bio-Techne
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NBP1-31432

Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human

Cited:

Human, Primate - Macaca mulatta (Rhesus Macaque)

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated, Western Blot

Cited:

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human SAMHD1. The exact sequence is proprietary.

Reactivity Notes

Monkey reactivity reported in scientific literature (PMID: 24956595).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

72 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SAMHD1 Antibody

Knockout Validated: SAMHD1 Antibody [NBP1-31432]

Knockout Validated: SAMHD1 Antibody [NBP1-31432]

Knockout Validated: SAMHD1 Antibody [NBP1-31432] - Wild-type (WT) and SAMHD1 knockout (KO) HeLa cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with SAMHD1 antibody [N2C2], Internal. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
Western Blot: SAMHD1 Antibody [NBP1-31432]

Western Blot: SAMHD1 Antibody [NBP1-31432]

Western Blot: SAMHD1 Antibody [NBP1-31432] - Sample (30 ug of whole cell lysate) A: THP-1 7.5% SDS PAGE, antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: SAMHD1 Antibody [NBP1-31432]

Immunocytochemistry/ Immunofluorescence: SAMHD1 Antibody [NBP1-31432]

Immunocytochemistry/Immunofluorescence: SAMHD1 Antibody [NBP1-31432] - Paraformaldehyde-fixed HeLa, using antibody at 1:500 dilution.

Applications for SAMHD1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SAMHD1

Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling

Long Name

SAM Domain and HD Domain 1

Alternate Names

AGS5, CHBL2, DCIP, HDDC1, MOP-5, SBBI88

Gene Symbol

SAMHD1

Additional SAMHD1 Products

Product Documents for SAMHD1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SAMHD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.