SAMHD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47292

Novus Biologicals, part of Bio-Techne
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NBP2-47292
NBP2-47292-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SAMHD1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: DDSPRTPSNTPSAEADWSPGLELHPDYKTWGPEQVCSFLRRGGFEEPVLLKNIRENEITGALLPCLDESRFENLGVSSLGERKKLLSYIQRLVQIHVDTMKVI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SAMHD1 Antibody

Western Blot: SAMHD1 Antibody [NBP2-47292]

Western Blot: SAMHD1 Antibody [NBP2-47292]

Western Blot: SAMHD1 Antibody [NBP2-47292] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human Analysis of liver tissue. Lane 6: Human tonsil tissue.
Immunocytochemistry/ Immunofluorescence: SAMHD1 Antibody [NBP2-47292]

Immunocytochemistry/ Immunofluorescence: SAMHD1 Antibody [NBP2-47292]

Immunocytochemistry/Immunofluorescence: SAMHD1 Antibody [NBP2-47292] - Staining of human cell line CACO-2 shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: SAMHD1 Antibody [NBP2-47292]

Immunohistochemistry-Paraffin: SAMHD1 Antibody [NBP2-47292]

Immunohistochemistry-Paraffin: SAMHD1 Antibody [NBP2-47292] - Staining of human skeletal muscle shows low expression as expected.
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Applications for SAMHD1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SAMHD1

Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling

Long Name

SAM Domain and HD Domain 1

Alternate Names

AGS5, CHBL2, DCIP, HDDC1, MOP-5, SBBI88

Gene Symbol

SAMHD1

Additional SAMHD1 Products

Product Documents for SAMHD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SAMHD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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