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SARS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20262

Novus Biologicals, part of Bio-Techne
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NBP2-20262

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human SARS2. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (84%).

Localization

Mitochondrion matrix

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SARS2 Antibody

Western Blot: SARS2 Antibody [NBP2-20262]

Western Blot: SARS2 Antibody [NBP2-20262]

Western Blot: SARS2 Antibody [NBP2-20262] - Sample (30 ug of whole cell lysate) A: MCF-7 7. 5% SDS PAGE gel, diluted at 1:5000.
Immunocytochemistry/ Immunofluorescence: SARS2 Antibody [NBP2-20262]

Immunocytochemistry/ Immunofluorescence: SARS2 Antibody [NBP2-20262]

Immunocytochemistry/Immunofluorescence: SARS2 Antibody [NBP2-20262] - SKNSH cells were fixed in 2% paraformaldehyde/culture medium at 37 C for 15 min.Green: SARS2 protein stained by SARS2 antibody [N1C1] diluted at 1:500.Blue: Hoechst 33342 staining.
Immunohistochemistry-Paraffin: SARS2 Antibody [NBP2-20262]

Immunohistochemistry-Paraffin: SARS2 Antibody [NBP2-20262]

Immunohistochemistry-Paraffin: SARS2 Antibody [NBP2-20262] - Immunohistochemical analysis of paraffin-embedded gastric ca, using antibody at 1:500 dilution.

Applications for SARS2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SARS2

This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

Alternate Names

EC 6.1.1.11, FLJ20450, mitochondrial seryl-tRNA synthetase, mtSerRS, SARS, serine tRNA ligase 2, mitochondrial, Serine--tRNA ligase, serine-tRNA ligase, mitochondrial, SerRS, SerRSmtSARSM, SERS, seryl-tRNA synthetase 2, seryl-tRNA synthetase 2, mitochondrial, seryl-tRNA synthetase, mitochondrial, Seryl-tRNA(Ser/Sec) synthetase, SYS

Gene Symbol

SARS2

UniProt

Additional SARS2 Products

Product Documents for SARS2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SARS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.