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Scn2b Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-82340

Novus Biologicals, part of Bio-Techne
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NBP2-82340-0.1ml

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of Mouse SCN2B. Peptide sequence: TVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKMDG The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Scn2b Antibody

Western Blot: Scn2b Antibody [NBP2-82340]

Western Blot: Scn2b Antibody [NBP2-82340]

Western Blot: Scn2b Antibody [NBP2-82340] - Host: Rabbit. Target Name: SCN2B. Sample Tissue: Mouse Thymus lysates. Antibody Dilution: 1ug/ml

Applications for Scn2b Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Scn2b

Voltage-gated sodium channels (NaV) are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. They are also expressed at low levels in non-excitable cells, where their physiological role is unclear. Structurally, Nav channels are composed of one pore-forming alpha-subunit, which may be associated with either one or more beta-subunits. alpha-subunits are composed for four homologous domains, each of which contains six transmembrane segments. The fourth transmembrane loop (S4) acts as the 'voltage sensor' and is activated by changes in membrane potential. S4 is also involved in channel gating.

Alternate Names

neuronal voltage-gated sodium channel beta 2 subunit, sodium channel beta 2 subunit, sodium channel subunit beta-2, sodium channel, voltage-gated, type II, beta, sodium channel, voltage-gated, type II, beta polypeptide

Gene Symbol

SCN2B

Additional Scn2b Products

Product Documents for Scn2b Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Scn2b Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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