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SCN4B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86057

Novus Biologicals, part of Bio-Techne
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NBP1-86057

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LLPCTFSSCFGFEDLHFRWTYNSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SCN4B Antibody

Western Blot: SCN4B Antibody [NBP1-86057]

Western Blot: SCN4B Antibody [NBP1-86057]

Western Blot: SCN4B Antibody [NBP1-86057] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: SCN4B Antibody [NBP1-86057]

Immunohistochemistry-Paraffin: SCN4B Antibody [NBP1-86057]

Immunohistochemistry-Paraffin: SCN4B Antibody [NBP1-86057] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: SCN4B Antibody [NBP1-86057]

Immunohistochemistry-Paraffin: SCN4B Antibody [NBP1-86057]

Immunohistochemistry-Paraffin: SCN4B Antibody [NBP1-86057] - Staining of human cerebellum shows moderate cytoplasmic positivity in purkinje cells.

Applications for SCN4B Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SCN4B

The protein encoded by the SCN4B gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.

Alternate Names

sodium channel beta-4 subunit, sodium channel subunit beta-4, sodium channel, voltage-gated, type IV, beta

Gene Symbol

SCN4B

Additional SCN4B Products

Product Documents for SCN4B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SCN4B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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